In a recent study researchers found “RESULTS: Testosterone, LH and FSH were significantly increased at the high dose of 7-methoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one treatment. The high and low dose of 7-methoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one treatment significantly enhanced the activity of NOS (P < ). CONCLUSION: 7-methoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one could increase androgen, gonadotropin and nitric oxide synthase (NOS) activity. It suggested that 7-methoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one had androgen-like effect and gonadotropin-like effect.” OSTA-PLEX® is the most advanced muscle building agent on the market today. The pSARM effect in OSTA-PLEX® along with the 19-NorDhea and advanced delivery matrix give OSTA-PLEX® the anabolic punch to build muscle! There has never been anything like OSTA-PLEX® for increasing size and strength!
Anabolic androgenic steroids (AAS) were initially created for therapeutic purposes, and synthetic derivatives of the male hormone testosterone. Due its great anabolic effects, these drugs are being used on a large scale, for the improvement of sports performance. In this present study, we aim to show the history of it’ use, present their mechanisms of action, more particularly its use correlate with improved body composition, muscle mass, aerobic capacity and verify their possible side effects, analyzing their use therapeutic and indiscriminate, through direct scientific research with the sports. Sources were reviewed scientific the following search engines: PUBMED, LILACS and SCIELO. The results showed that in presence of a suitable AAS and diet can contribute to increases in body weight, particularly lean body mass and muscle strength gains achieved by high intensity exercise, these effects can be further potentiated, the use of supraphysiological doses, but in the aspect of aerobic power, there are not scientific evidence to support their improvement. Regarding side effects, the use of AAS, is related to several complications in the liver, cardiovascular system, reproductive system and psychological characteristics, always assigned by the non-therapeutic and abuse of AAS. Thus we conclude that the use of AAS, are directly linked to gains muscle mass, strength, as well several side effects, always assigned to abusive and indiscriminate doses, it is noteworthy that the scientific literature, still has a certain lack of studies, mainly randomized, controlled, with supraphysiological doses in human, so many effects are still unknown.
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In November 1942, the Italian cyclist Fausto Coppi took "seven packets of amphetamine" to beat the world hour record on the track.  In 1960, the Danish rider Knud Enemark Jensen collapsed during the 100 km team time trial at the Olympic Games in Rome and died later in hospital. The autopsy showed he had taken amphetamine and another drug, Ronicol , which dilates the blood vessels. The chairman of the Dutch cycling federation, Piet van Dijk, said of Rome that "dope – whole cartloads – [were] used in such royal quantities." 
In November 1942, the Italian cyclist Fausto Coppi took "seven packets of amphetamine" to beat the world hour record on the track.  In 1960, the Danish rider Knud Enemark Jensen collapsed during the 100 km team time trial at the Olympic Games in Rome and died later in hospital. The autopsy showed he had taken amphetamine and another drug, Ronicol , which dilates the blood vessels. The chairman of the Dutch cycling federation, Piet van Dijk, said of Rome that "dope – whole cartloads – [were] used in such royal quantities."