It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
Masteron Enanthate is dosed at 200mgs/ml, and comes in a 10ml multi use vial, with (of course) the enanthate ester instead of Masteron’s traditional propionate ester. Though this particular compound acts just like the one with the propionate ester, in almost all respects.
The higher concentration (200mgs/ml) and longer ester (enanthate) allow us to do several interesting things with this compound.
One I’ve heard of is people running a gram per week of it, and that would only require two shots! Another thing I’ve seen is people using this with a long estered Tren and Test (along with an ancillary compound like Letro) and having a great cutting cycle that only requires a 1-2 day a week injection schedule.
The best time to use Masteron Enanthate is when the individual is already very lean hence why it is so commonly used in cutting cycles. Usually, bodybuilders use Masteron in the last half of preparation for a competition after they have already dropped a lot of fat. The drug then helps lost the last few pounds which can be tricky to get rid of. Masteron Enanthate can still be a good idea to anyone who is not professional yet. Though, the same effects will not be experienced it can have benefits. If you are not already quite lean then the effects will not be noticeable if any is seen at all.