We have assessed the gonadotropin, TSH and PRL responses to the non aromatizable androgens, mesterolone and fluoxymestrone, in 27 patients with primary testicular failure. All patients were given a bolus of LHRH (100 micrograms) and TRH (200 micrograms) at zero time. Nine subjects received a further bolus of TRH at 30 mins. The latter were then given mesterolone 150 mg daily for 6 weeks. The remaining subjects received fluoxymesterone 5 mg daily for 4 weeks and 10 mg daily for 2 weeks. On the last day of the androgen administration, the subjects were re-challenged with LHRH and TRH according to the identical protocol. When compared to controls, the patients had normal circulating levels of testosterone, estradiol, PRL and thyroid hormones. However, basal LH, FSH and TSH levels, as well as gonadotropin responses to LHRH and TSH and PRL responses to TRH, were increased.
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5. Zinc . If you are zinc deficient, the evidence shows that it can be a root cause for low DHT. Furthermore, if this is your underlying issue, you can significantly raise your DHT just by taking this inexpensive supplement. Try to avoid the zinc oxide form, since it is so poorly absorbed. For some of the studies, see my link on Zinc and DHT . (A zinc deficiency can also lead to very low testosterone levels as well.) I do have some cautions though about taking too much zinc and I urge anyone taking supplemental zinc to scan through this page: The Potential Dangers of Zinc .